Human Insulin+insulin Isophane
About Human Insulin+insulin Isophane
Human Insulin+insulin Isophane is used for the treatment of both type 1 and type 2 diabetes mellitus. Diabetes mellitus is a condition that affects the way the body processes glucose. In Diabetes Mellitus Type 1, the body does not make enough insulin to control blood sugar levels. In Diabetes Mellitus type 2, either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood), or there is resistance to the action of insulin. As a result, insulin is produced in large amounts, but it cannot act on the organs of the body.
Human Insulin+insulin Isophane is a combination of two drugs: Human insulin (a short-acting type of insulin) and Insulin isophane (intermediate-acting). Human Insulin+insulin Isophane suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells; thereby, Human Insulin+insulin Isophane ensures rapid and consistent sugar control.
Take Human Insulin+insulin Isophane as advised by your doctor. If you are not well trained to self-administer Human Insulin+insulin Isophane, ask your healthcare professional to administer it. In some cases, Human Insulin+insulin Isophane may cause certain common side effects like an allergic reaction at the site of injection, hypoglycemia (low blood glucose level), itching, lipodystrophy (skin thickening or pits at the injection site), oedema (swelling), rashes, and weight gain. Most of these side effects of Human Insulin+insulin Isophane do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Consult your doctor before taking Human Insulin+insulin Isophane if you are pregnant or breastfeeding. Human Insulin+insulin Isophane may cause drowsiness, so drive with caution. Avoid alcohol consumption along with Human Insulin+insulin Isophane as it may cause unpleasant side effects. Human Insulin+insulin Isophane should be given to children only if prescribed by the doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Human Insulin+insulin Isophane is a cold chain medicine, it has to be stored in the refrigerator between 2-8°C else its efficiency may be lost. Do not store in the freezer.
Uses of Human Insulin+insulin Isophane
Medicinal Benefits
Human Insulin+insulin Isophane is a combination of two drugs: Human insulin (a short-acting type of insulin) and Insulin isophane (intermediate-acting). Human Insulin+insulin Isophane is used for the treatment of both type 1 and type 2 diabetes mellitus. Human Insulin+insulin Isophane suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells; thereby, Human Insulin+insulin Isophane ensures rapid and consistent sugar control. Human Insulin+insulin Isophane helps in improving glycaemic control, which in turn decreases the risk of progression of diabetes complications like damage to the retina (retinopathy), damage to the kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer.
Directions for Use
Storage
Side Effects of Human Insulin+insulin Isophane
Allergic reaction at the site of injection
Hypoglycemia (low blood glucose level)
Itching
Lipodystrophy (skin thickening or pits at the injection site)
Oedema (swelling)
Rashes
Weight gain
Drug Warnings
Do not take Human Insulin+insulin Isophane if you are allergic to any of the contents. Inform your doctor if you have hypoglycemia (low blood glucose levels), hypokalemia (low levels of potassium in the blood), heart, kidney or liver problems. Consult a doctor before taking Human Insulin+insulin Isophane if you are pregnant or breastfeeding. Human Insulin+insulin Isophane may cause dizziness, so drive only if you are alert. You are recommended not to consume alcohol as it may cause unpleasant side effects. Care should be taken when you are travelling across more than 2 time zones; your doctor may adjust your insulin schedule.
Drug Interactions
Drug-Drug Interaction: Human Insulin+insulin Isophane may interact with medicines such as pain killer (aspirin), antibiotic (ciprofloxacin), bronchodilators (albuterol, ipratropium), diuretic (furosemide), anti-hypertensive (metoprolol), anti-depressant (sertraline), oral hypoglycemic agents, monoamine oxidase inhibitors, anabolic steroids, glucocorticoids, thyroid hormones and sympathomimetics.
Drug-Food Interaction: Avoid consumption of alcohol along with Human Insulin+insulin Isophane as it may lead to unpleasant side effects.
Drug-Disease Interaction: Inform your doctor if you have kidney disease, liver disease, low potassium level (hypokalaemia), and low blood sugar/glucose level (hypoglycemia).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol along with Human Insulin+insulin Isophane to avoid unpleasant side effects. Alcohol may cause increased drowsiness.
Pregnancy
safe if prescribedIt is safe to use Human Insulin+insulin Isophane during pregnancy if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.
Breast Feeding
safe if prescribedIt is safe to use Human Insulin+insulin Isophane by breastfeeding mothers if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.
Driving
cautionHuman Insulin+insulin Isophane may cause drowsiness and hypoglycemia (low blood sugar). Therefore, drive only if you are alert.
Liver
cautionHuman Insulin+insulin Isophane should be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.
Kidney
cautionHuman Insulin+insulin Isophane should be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.
Children
safe if prescribedHuman Insulin+insulin Isophane can be given safely to children provided the dose has been prescribed by a child specialist.
Habit Forming
Diet & Lifestyle Advise
- Include foods rich in healthy carbohydrates and fiber, fruits, whole grains, and vegetables in your diet.
- Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
- Follow a healthy diet and walk for at least a few minutes to complement treatment with Human Insulin+insulin Isophane.
- Maintain a healthy weight by exercising regularly.
- Rest properly, and avoid stress by doing meditation or yoga.
Special Advise
If you feel any symptoms of hypoglycemia (fatigue, dizziness, confusion, heart palpitations, shakiness and anxiety), consult your doctor immediately.
Patients Concern
Disease/Condition Glossary
Diabetes: Diabetes is a chronic or lifelong disease that prevents the body from utilizing insulin properly. Insulin is the hormone that controls sugar levels in the blood. Diabetes is a condition in which blood glucose levels are above normal. It is of two types: type-1 and type-2 diabetes. Type-1 diabetes is a condition in which the pancreas produces little or no insulin. Type-2 diabetes affects the way body processes the sugar. Symptoms of diabetes include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.
FAQs
Human Insulin+insulin Isophane is used for the treatment of both type 1 and type 2 diabetes mellitus.
Human Insulin+insulin Isophane suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells, thereby Human Insulin+insulin Isophane ensures rapid and consistent sugar control.Â
Human Insulin+insulin Isophane may sometimes lower the blood glucose levels more than normal, leading to hypoglycaemia. Regularly monitor your blood sugar levels while taking Human Insulin+insulin Isophane. Hypoglycaemia symptoms include headache, drowsiness, cold sweat, feeling sick, unusual tiredness or weakness, and visual disturbances.
Do not stop taking Human Insulin+insulin Isophane without consulting your doctor on your own as it may cause an increase in blood glucose levels. Continue taking Human Insulin+insulin Isophane for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Human Insulin+insulin Isophane.
Maintain a healthy diet by regular intake of carbohydrates such as bread and products containing starch and sugar. Eat your meals regularly, and do not exercise heavily for longer durations with an empty stomach.
Hypoglycaemia may occur following prolonged or severe exercise, during illness, alcohol consumption, low food intake, or when Human Insulin+insulin Isophane is taken along with other antidiabetic medicines.
Side effects of Human Insulin+insulin Isophane include allergic reaction at the site of injection, hypoglycemia (low blood glucose level), itching, lipodystrophy (skin thickening or pits at the injection site), oedema (swelling), rashes, and weight gain. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
The injection site should be changed to prevent skin changes like lumps under the skin. Human Insulin+insulin Isophane may not work well if injected into the lumpy area.
Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.
Hypoglycaemia (low blood sugar) may occur because you inject too much insulin, miss or delay meals, do not eat enough, eat food containing less carbohydrate than normal, drink alcohol, lose carbohydrates due to vomiting or diarrhoea, do more exercise than usual or a different type of physical activity, are recovering from an injury, illness, operation or stress, or are taking/have stopped taking other medicines.
Symptoms of high blood sugar include feeling thirsty, increased urination, weakness or tiredness, blurred vision and weight loss.
Human Insulin+insulin Isophane is to be injected below the skin (subcutaneously). The best areas to inject Human Insulin+insulin Isophane are on your stomach, upper arm, upper thigh, or buttocks.
Unopened vials are to be refrigerated between 2°C and 8°C. Opened vials (in-use) may be stored not above 25ºC for a maximum of 4 weeks. The used needle should be placed in a puncture-resistant disposable container and disposed of properly as directed by your healthcare provider.
Avoid drinking alcohol while taking Human Insulin+insulin Isophane as it might lower blood sugar levels and cause hypoglycaemia.
